Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout
Y Kawamura, H Nakaoka, A Nakayama… - Annals of the …, 2019 - ard.bmj.com
Objective The first ever genome-wide association study (GWAS) of clinically defined gout
cases and asymptomatic hyperuricaemia (AHUA) controls was performed to identify novel …
cases and asymptomatic hyperuricaemia (AHUA) controls was performed to identify novel …
[HTML][HTML] Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals
Gout is a common arthritis caused by elevated serum uric acid (SUA) levels. Here we
investigated loci influencing SUA in a genome-wide meta-analysis with 121,745 Japanese …
investigated loci influencing SUA in a genome-wide meta-analysis with 121,745 Japanese …
Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically …
A Nakayama, M Nakatochi, Y Kawamura… - Annals of the …, 2020 - ard.bmj.com
Objectives Genome-wide meta-analyses of clinically defined gout were performed to identify
subtype-specific susceptibility loci. Evaluation using selection pressure analysis with these …
subtype-specific susceptibility loci. Evaluation using selection pressure analysis with these …
Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels
T Higashino, K Morimoto, H Nakaoka… - Annals of the …, 2020 - ard.bmj.com
Organic anion transporter 10 (OAT10), also known as SLC22A13, has hitherto been
identified as a urate transporter by in vitro analyses. 1 Despite the reported expression of …
identified as a urate transporter by in vitro analyses. 1 Despite the reported expression of …
Isolated spontaneous dissection of the celiac artery: report of two cases
Y Takayama, M Takao, T Inoue, F Yoshimi… - Annals of Vascular …, 2014 - jstage.jst.go.jp
Isolated spontaneous dissection of the celiac artery (DCA) is extremely rare and its
therapeutic strategy is still not established. We report two cases of DCA, in which 58-year …
therapeutic strategy is still not established. We report two cases of DCA, in which 58-year …
[HTML][HTML] Assessing the development status of intraoperative fluorescence imaging for perfusion assessments, using the IDEAL framework
T Ishizawa, P McCulloch, D Muehrcke… - BMJ Surgery …, 2021 - ncbi.nlm.nih.gov
Objectives Intraoperative fluorescence imaging is currently used in a variety of surgical fields
for four main purposes: assessing tissue perfusion; identifying/localizing cancer; mapping …
for four main purposes: assessing tissue perfusion; identifying/localizing cancer; mapping …
[HTML][HTML] A common variant of LDL receptor related protein 2 (LRP2) gene is associated with gout susceptibility: a meta-analysis in a Japanese population
A Akashi, A Nakayama, Y Kamatani, T Higashino… - Human Cell, 2020 - Springer
Gout, which results from elevated serum uric acid (SUA), is a common form of arthritis that is
induced by urate crystals. A single nucleotide polymorphism, rs2544390, of LDL receptor …
induced by urate crystals. A single nucleotide polymorphism, rs2544390, of LDL receptor …
[HTML][HTML] Probe-based confocal laser endomicroscopy for real-time evaluation of colorectal liver metastasis in resected surgical specimens
M Takao, Y Kawaguchi, M Matsumura, Y Kazami… - Human Cell, 2023 - Springer
Probe-based confocal laser endomicroscopy (pCLE) enables real-time examination of
tissue structure. This study investigated pCLE with or without fluorescein sodium for the …
tissue structure. This study investigated pCLE with or without fluorescein sodium for the …
[HTML][HTML] Both variants of A1CF and BAZ1B genes are associated with gout susceptibility: a replication study and meta-analysis in a Japanese population
M Kawaguchi, A Nakayama, Y Aoyagi, T Nakamura… - Human Cell, 2021 - Springer
Gout is a common type of acute arthritis that results from elevated serum uric acid (SUA)
levels. Recent genome-wide association studies (GWASs) have revealed several novel …
levels. Recent genome-wide association studies (GWASs) have revealed several novel …
[HTML][HTML] A rare case of localized peliosis hepatis during adjuvant chemotherapy including oxaliplatin mimicking a liver metastasis of colon cancer
A Dejima, Y Seyama, D Nakano, M Takao… - Surgical Case …, 2023 - Springer
Background Oxaliplatin-based regimens are commonly used as adjuvant chemotherapy
following surgery for colorectal cancer. Adverse events associated with oxaliplatin include …
following surgery for colorectal cancer. Adverse events associated with oxaliplatin include …