Importance The incidence of early-onset colorectal cancer (younger than 50 years) is rising
globally, the reasons for which are unclear. It appears to represent a unique disease …

Regardless of how the problem is examined, diverticular disease is a significant burden for
both patients and healthcare systems. In Western and industrialized nations, diverticulosis of …

Perianal fistulizing Crohn's disease (PFCD) is associated with significant morbidity and
might negatively impact the quality of life of CD patients. In the last two decades, the …

Abstract γδ T cells account for a large fraction of human intestinal intraepithelial lymphocytes
(IELs) endowed with potent antitumor activities. However, little is known about their origin …

Aim The use of robotic techniques in colorectal surgery is increasing. Recently, the
Senhance™ surgical robotic system was introduced as a novel robotic platform designed to …

Objective Older patients with cancer value functional outcomes as much as survival, but
surgical studies lack functional recovery (FR) data. The value of a standardized frailty …

Importance Delays in screening programs and the reluctance of patients to seek medical
attention because of the outbreak of SARS-CoV-2 could be associated with the risk of more …

Background A third of patients with colorectal cancer who are eligible for surgery in high-
income countries have concomitant anaemia associated with adverse outcomes. We aimed …

Colorectal cancer is a major cause of cancer-related death in Western countries and is
associated with increased numbers of lymphatic vessels (LV) and tumor-associated …

Perianal fistulising Crohn's disease is an aggressive disease phenotype that can have a
substantial detrimental impact on patients' quality of life. Current biological understanding of …