[HTML][HTML] The current state of animal models in research: A review

NB Robinson, K Krieger, FM Khan, W Huffman… - International Journal of …, 2019 - Elsevier
Animal models have provided invaluable information in the pursuit of medical knowledge
and alleviation of human suffering. The foundations of our basic understanding of disease …

2021 The American Association for Thoracic Surgery expert consensus document: surgical treatment of acute type A aortic dissection

SC Malaisrie, WY Szeto, M Halas, LN Girardi… - The Journal of thoracic …, 2021 - jtcvs.org
Acute aortic dissection (AD) involves the ascending aorta in approximately two-thirds of
patients. 1, 2 Chest pain is the most common feature, but clinical presentation can be varied …

Mechanisms, consequences, and prevention of coronary graft failure

M Gaudino, C Antoniades, U Benedetto, S Deb… - Circulation, 2017 - Am Heart Assoc
Graft failure occurs in a sizeable proportion of coronary artery bypass conduits. We herein
review relevant current evidence to give an overview of the incidence, pathophysiology, and …

2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint …

Writing Committee Members, EM Isselbacher… - Journal of the American …, 2022 - jacc.org
Abstract Aim The “2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic
Disease” provides recommendations to guide clinicians in the diagnosis, genetic evaluation …

[HTML][HTML] Radial-artery or saphenous-vein grafts in coronary-artery bypass surgery

M Gaudino, U Benedetto, S Fremes… - … England Journal of …, 2018 - Mass Medical Soc
Background The use of radial-artery grafts for coronary-artery bypass grafting (CABG) may
result in better postoperative outcomes than the use of saphenous-vein grafts. However …

Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised …

MS Avidan, HR Maybrier, AB Abdallah, E Jacobsohn… - The Lancet, 2017 - thelancet.com
Background Delirium is a common and serious postoperative complication. Subanaesthetic
ketamine is often administered intraoperatively for postoperative analgesia, and some …

Association of radial artery graft vs saphenous vein graft with long-term cardiovascular outcomes among patients undergoing coronary artery bypass grafting: a …

M Gaudino, U Benedetto, S Fremes, K Ballman… - Jama, 2020 - jamanetwork.com
Importance Observational studies have suggested that the use of radial artery grafts for
coronary artery bypass grafting may improve clinical outcomes compared with the use of …

Sex differences in outcomes after coronary artery bypass grafting: a pooled analysis of individual patient data

M Gaudino, A Di Franco, JH Alexander… - European heart …, 2022 - academic.oup.com
Aims Data suggest that women have worse outcomes than men after coronary artery bypass
grafting (CABG), but results have been inconsistent across studies. Due to the large …

Overall and cause-specific mortality in randomized clinical trials comparing percutaneous interventions with coronary bypass surgery: a meta-analysis

M Gaudino, I Hameed, ME Farkouh… - JAMA internal …, 2020 - jamanetwork.com
Importance Mortality is a common outcome in trials comparing percutaneous coronary
intervention (PCI) with coronary artery bypass grafting (CABG). Controversy exists regarding …

Management strategies for type A dissection complicated by peripheral vascular malperfusion

LN Girardi, KH Krieger, LY Lee, CA Mack… - The Annals of thoracic …, 2004 - Elsevier
BACKGROUND: End-organ malperfusion is a dreaded complication of type A aortic
dissections. Different strategies have been proposed to manage this complex cohort of …