User profiles for "author:Konrad Wagstyl"

Konrad Wagstyl

University College London
Verified email at ucl.ac.uk
Cited by 3900

Adolescence is associated with genomically patterned consolidation of the hubs of the human brain connectome

KJ Whitaker, PE Vértes… - Proceedings of the …, 2016 - National Acad Sciences
How does human brain structure mature during adolescence? We used MRI to measure
cortical thickness and intracortical myelination in 297 population volunteers aged 14–24 y …

[PDF][PDF] Morphometric similarity networks detect microscale cortical organization and predict inter-individual cognitive variation

J Seidlitz, F Váša, M Shinn, R Romero-Garcia… - Neuron, 2018 - cell.com
Macroscopic cortical networks are important for cognitive function, but it remains challenging
to construct anatomically plausible individual structural connectomes from human …

[HTML][HTML] Microstructural and functional gradients are increasingly dissociated in transmodal cortices

C Paquola, R Vos De Wael, K Wagstyl… - PLoS …, 2019 - journals.plos.org
While the role of cortical microstructure in organising neural function is well established, it
remains unclear how structural constraints can give rise to more flexible elements of …

[HTML][HTML] Obesity associated with increased brain age from midlife

L Ronan, AF Alexander-Bloch, K Wagstyl, S Farooqi… - Neurobiology of …, 2016 - Elsevier
Common mechanisms in aging and obesity are hypothesized to increase susceptibility to
neurodegeneration, however, direct evidence in support of this hypothesis is lacking. We …

Gene transcription profiles associated with inter-modular hubs and connection distance in human functional magnetic resonance imaging networks

PE Vértes, T Rittman, KJ Whitaker… - … of the Royal …, 2016 - royalsocietypublishing.org
Human functional magnetic resonance imaging (fMRI) brain networks have a complex
topology comprising integrative components, eg long-distance inter-modular edges, that are …

[HTML][HTML] Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders

J Seidlitz, A Nadig, S Liu, RAI Bethlehem… - Nature …, 2020 - nature.com
Neurodevelopmental disorders have a heritable component and are associated with region
specific alterations in brain anatomy. However, it is unclear how genetic risks for …

Artificial intelligence for the detection of focal cortical dysplasia: Challenges in translating algorithms into clinical practice

L Walger, S Adler, K Wagstyl, L Henschel, B David… - …, 2023 - Wiley Online Library
Focal cortical dysplasias (FCDs) are malformations of cortical development and one of the
most common pathologies causing pharmacoresistant focal epilepsy. Resective …

[HTML][HTML] Cortical thickness gradients in structural hierarchies

K Wagstyl, L Ronan, IM Goodyer, PC Fletcher - Neuroimage, 2015 - Elsevier
MRI, enabling in vivo analysis of cortical morphology, offers a powerful tool in the
assessment of brain development and pathology. One of the most ubiquitous measures …

Interpretable surface-based detection of focal cortical dysplasias: a Multi-centre Epilepsy Lesion Detection study

H Spitzer, M Ripart, K Whitaker, F D'Arco, K Mankad… - Brain, 2022 - academic.oup.com
One outstanding challenge for machine learning in diagnostic biomedical imaging is
algorithm interpretability. A key application is the identification of subtle epileptogenic focal …

[HTML][HTML] BigBrain 3D atlas of cortical layers: Cortical and laminar thickness gradients diverge in sensory and motor cortices

K Wagstyl, S Larocque, G Cucurull, C Lepage… - PLoS …, 2020 - journals.plos.org
Histological atlases of the cerebral cortex, such as those made famous by Brodmann and
von Economo, are invaluable for understanding human brain microstructure and its …