The beta cell in type 2 diabetes

AA Christensen, M Gannon - Current diabetes reports, 2019 - Springer
Abstract Purpose of Review This review summarizes the alterations in the β-cell observed in
type 2 diabetes (T2D), focusing on changes in β-cell identity and mass and changes …

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

AM Haidet-Phillips, ME Hester, CJ Miranda… - Nature …, 2011 - nature.com
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease, with astrocytes
implicated as contributing substantially to motor neuron death in familial (F) ALS 1, 2, 3, 4, 5 …

vanishing tassel2 Encodes a Grass-Specific Tryptophan Aminotransferase Required for Vegetative and Reproductive Development in Maize

KA Phillips, AL Skirpan, X Liu, A Christensen… - The Plant …, 2011 - academic.oup.com
Auxin plays a fundamental role in organogenesis in plants. Multiple pathways for auxin
biosynthesis have been proposed, but none of the predicted pathways are completely …

Molecular characterization of patient-derived human pancreatic tumor xenograft models for preclinical and translational development of cancer therapeutics

M Mattie, A Christensen, MS Chang, W Yeh, S Said… - Neoplasia, 2013 - Elsevier
Preclinical evaluation of novel cancer agents requires models that accurately reflect the
biology and molecular characteristics of human tumors. Molecular profiles of eight …

Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy

YR Feliz-Mosquea, AA Christensen, AS Wilson… - Breast cancer research …, 2018 - Springer
Background A perennial challenge in systemic cytotoxic cancer therapy is to eradicate
primary tumors and metastatic disease while sparing normal tissue from off-target effects of …

[HTML][HTML] Effect of single-and double-layer cesarean section closure on residual myometrial thickness and isthmocele-a systematic review and meta-analysis

GJ Marchand, A Masoud, A King, S Ruther… - Turkish Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: To determine the incidence of isthmocele, its effect on residual myometrial
thickness (RMT), and other complications of Cesarean delivery (CD) in relation to single-and …

MADS‐box gene expression and implications for developmental origins of the grass spikelet

JC Preston, A Christensen… - American Journal of …, 2009 - Wiley Online Library
Basic questions regarding the origin and evolution of grass (Poaceae) inflorescence
morphology remain unresolved, including the developmental genetic basis for evolution of …

Cardiac Protein Kinase D1 ablation alters the myocytes β-adrenergic response

JM Hernandez, CY Ko, AR Mandel, EY Shen… - Journal of Molecular and …, 2023 - Elsevier
Abstract β-adrenergic (β-AR) signaling is essential for the adaptation of the heart to exercise
and stress. Chronic stress leads to the activation of Ca 2+/calmodulin-dependent kinase II …

Safety of prophylactic anticoagulation at a pediatric hospital

J Stem, A Christensen, D Davis… - Journal of pediatric …, 2013 - journals.lww.com
The importance of preventing venous thromboembolism (VTE) in hospitalized adults is well
recognized. We recently developed and published our institutional guidelines for the …

[HTML][HTML] Contained and uncontained morcellation in hysterectomy and myomectomy: A systematic review and meta-analysis

G Marchand, A Masoud, A Christensen… - Turkish Journal of …, 2021 - ncbi.nlm.nih.gov
We sought to analyze all high-quality studies available regarding the possible differences in
contained and uncontained techniques for morcellation of fibroids and uteri. We …