Logistic regression for factors associated with MRI-targeted biopsy diagnosis of indolent and clinically significant prostate cancer
| Indolent cancer | Significant cancer | |||
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Covariable | ||||
| Asian-American | 0.37 (0.15 to 0.91) | 0.030 | 0.30 (0.14 to 0.65) | 0.002 |
| Biopsy naïve | 1.14 (0.73 to 1.80) | 0.566 | 2.25 (1.45 to 3.49) | <0.001 |
| PI-RADS 3* | – | – | – | – |
| PI-RADS 4 | 1.16 (0.71 to 1.89) | 0.558 | 3.82 (2.27 to 6.45) | <0.001 |
| PI-RADS 5 | 0.77 (0.39 to 1.52) | 0.450 | 7.69 (4.14 to 14.30) | <0.001 |
| Age (years) | 0.97 (0.95 to 0.999) | 0.045 | 1.07 (1.04 to 1.11) | <0.001 |
| Body mass index (kg/m2) | 0.98 (0.93 to 1.05) | 0.604 | 1.03 (0.97 to 1.09) | 0.362 |
| PSAD (ng/mL/cm3) | 0.82 (0.52 to 1.30) | 0.401 | 4.02 (2.57 to 6.29) | <0.001 |
Non-AA is the referent for AA. Prior negative biopsy is the referent for biopsy naïve.
*PI-RADS 3 as referent.
†PSAD <0.15 as referent.
AA, Asian-American; PI-RADS, Prostate Imaging-Reporting and Data System; PSAD, prostate-specific antigen density.