Table 1

Costs and drivers of counterfactual studies: The TVT CRN*

Counterfactual studiesTotal subjectsTotal sitesStudy duration (years)Evaluations per yearTotal procedure countTotal cost per study
A200039515$ 21 949 424
B55027515$ 7 539 932
C170027515$ 18 814 232
D100028515$ 11 911 048
E20028515$ 4 165 448
F1000571017$ 17 798 692
G100029515$ 11 925 264
H1000571017$ 17 798 692
I100045515$ 12 152 720
J20037515$ 4 293 392
K10041515$ 3 382 056
L1000651017$ 17 979 140
M15029515$ 3 695 564
N15029515$ 3 695 564
O15029515$ 3 695 564
P10029515$ 3 211 464
  • *Note. The calculations assume all patients are treated inside USA, requiring inperson evaluations, and the study was not randomized and had no control group. The letters designating the individual studies correspond with the studies listed in table 3.