Table 1

Population covariate comparison (pre-match and post-match)

CovariateTotal study populationAfter propensity match
Mynx VCDAlternate VCDStd. Diff.Mynx VCDAlternate VCDStd. Diff.
(n=109,857)(n=925,355)(n=109,857)(n=109,857)
Age (years)65.19±11.9064.95±12.090.020065.19±11.9065.22±11.890.0026
Female gender34.12%30.49%0.077734.12%34.47%0.0072
Body mass index (kg/m2)
 <213.52%3.67%0.00803.52%3.55%0.0014
 ≥25 and <3035.7%37.0%0.028235.7%35.7%0.0003
 ≥3045.31%43.21%0.042345.31%45.38%0.0014
Diabetes39.1%35.3%0.079539.1%39.5%0.0084
Chronic lung disease16.3%13.5%0.078316.3%16.3%0.0022
Hypertension84.7%80.9%0.100184.7%84.8%0.0037
Baseline creatinine (mg/dL)1.19±1.031.16±0.950.06271.19±1.031.20±1.060.0095
Peripheral arterial disease12.7%9.7%0.096412.7%12.9%0.0047
Emergent procedure status11.7%17.7%0.169311.7%11.8%0.0018
NSTEMI on presentation17.17%19.25%0.054017.17%17.01%0.0040
Bivalirudin exposure66.9%61.8%0.106266.9%67.5%0.0119
Left main coronary artery PCI2.06%2.11%0.00372.06%2.00%0.0043
Number of vessels treated during index PCI1.42±0.701.44±0.730.02921.42±0.701.42±0.710.0049
Fluoroscopy time (min)12.33±9.7714.04±11.150.134012.33±9.7712.46±9.420.0102
Total number of PCI during admission1.04811.04670.00621.04811.04830.0006
  • Plus–minus values are means±SD. The standardised difference (the mean between-group difference divided by the SD) and was calculated to assess the relative imbalance between the exposed and unexposed groups, with values of less than 0.100 considered to be adequately balanced. The body mass index is the weight in kilograms divided by the square of the height in meters.

  • CAD, coronary artery disease; NSTEMI, non-ST elevation myocardial infarction; PCI, percutaneous coronary intervention; Std. Diff., absolute percentile standardized difference; VCD, vascular closure device.